• Principal Scientist (February 2019 – to-date) at NIIST-CSIR, Trivandrum
• Senior Scientist (February 2015 – February 2019) at NIIST-CSIR, Trivandrum
• Scientist (February 2012 – February 2015) at NIIST-CSIR, Trivandrum
• Ramanujan Fellow (October 2012 – September 2017) at CSIR-NIIST, Trivandrum
• Research Scientist II (2006 – 2012) at School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA.
• Postdoctoral Research Fellow (2004 – 2006) at School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA (Advisor: Professor Gary Schuster).
• Senior Research Fellow (2002-2004) and Junior Research Fellow (2000-2002) under CSIR-NET Fellowship at NIIST-CSIR, Trivandrum (Advisor: Dr. D. Ramaiah).
• JNCASR Research Fellow (1999-2000, 8 months) at NIIST-CSIR, Trivandrum (Advisor: Dr. D. Ramaiah).
• M. Sc. Project Fellow (1998, 4 months) at the Photosciences and Photonics Division, National Institute for Interdisciplinary Science & Technology (NIIST-CSIR), Trivandrum.

• Raman Fellowship (CSIR, Govt of India; 2020-2021)
• Ramanujan Fellowship (SERB, Govt of India; 2012)
• CSIR Senior Research Fellowship (CSIR; 2002)
• CSIR Junior research Fellowship (CSIR; 2000)
• JNCASR Research Fellow (JNCASR, Bangalore; 1999)

• Development of mRNA Platform for Vaccines and Biotherapeutics – Multi-institutional Project (Project Leader – CSIR-NIIST; MLP-0064; Rs. 64 Lakhs)
  Duration: 2 Years (2021-2023)
  Sponsoring Agency: CSIR (Healthcare Theme – COVID-19)
• Chromogenic Materials and Inks for Smart Coating and Printable Applications (Principal Investigator; MLP 0049; Rs.75 Lakhs)
  Duration: 3 Years (2020-2023)
  Sponsoring Agency: CSIR (Chemicals Theme – NCP)
• Large area opto-electronics for Australia and India: From materials to advanced devices (Team Member; GAP-138839)
  Duration: 3 Years (2018-2021)
  Sponsoring Agency: DST (AISRF), Govt. of India Team Member
• Translating Electrochromic Devices to 1’ × 1’ Dynamic Windows: Towards Industrial Smart Glass Technologies (Co-PI; MLP 0037)
  Duration: 1.5 Years (2020-2022)
  Sponsoring Agency: CSIR (Energy Theme – FTC)
• Advanced Materials Mission- Development of Advanced Materials and Devices for Opto-electronic, Biomedical and Strategic applications (Team Member; HCP 0030)
  Duration: 3 Years (2020-2023)
  Sponsoring Agency: CSIR (Mission Project)

Completed Projects

• COVID-19 ViralRNA detection kit with ultra-bright oligoprobes for the capture and detection of viralRNA via Lateral Flow based devices (Principal Investigator; MLP 0048; 39.00 Lakhs)
  Duration: 1 Year (2020-2021)
  Sponsoring Agency: CSIR (Healthcare Theme – COVID-19)
• Development of novel NIR absorbing sensitizers and their nano-conjugates for the multimodal cancer imaging and therapy (Principal Investigator, GAP 137539; 20 Lakhs)
  Duration: 3 Years (2017-2020)
  Sponsoring Agency: DBT, Govt of India
• New Materials for Improved, Cost-Effective Perovskite Solar Cells (Principal Investigator, GAP 136639; Rs.53.60 Lakhs)
  Duration: 3 Years (2015-2018)
  Funding Agency: DST – CERI
• Chromogenic Materials for Smart Coating Applications (Principal Investigator, MLP 0030; Rs.134.012 Lakhs)
  Duration: 2 Years (2018-2020)
  Funding Agency: CSIR (Chemicals Theme, NCP)
• Development of Cellular Sensors: Biocompatible fluorescent molecules for sensing and cellular imaging of pH, Zn2+ and reactive oxygen species (Principal Investigator, MLP 0027; Rs. 75 Lakhs)
  Duration: 1.5 Years (2018-2020)
  Funding Agency: CSIR (Healthcare Theme, FTT)
• Electrochromic devices for efficient energy management and utilization (Co-PI, MLP 0022)
  Duration: 1.5 Years (2018-2020)
  Funding Agency: CSIR (Energy Theme, FTT)
• Fused thiophene based FET devices for lung cancer VOC biomarker detection (Co-PI, MLP 0026; Rs. 50 Lakhs)
  Duration: 1.5 Years (2018-2020)
  Funding Agency: CSIR (Healthcare Theme, FTT)
• Mission mode program ‘Nano-biosensors and microfluidics for healthcare’ (Principal Investigator & National Additional Coordinator; HCP-0012)
  Duration: 3 Years (2017-2020)
  Sponsoring Agency: CSIR (Healthcare Theme, Mission Mode Project)
• Design and Synthesis of Multifunctional Organic-DNA Conjugates for Biomolecular Applications (Principal Investigator, GAP 133939; Rs. 54.15 Lakhs)
  Duration: 5 Years (2012-2017)
  Sponsoring Agency: SERB, Govt. of India (Ramanujan Fellowship Grant)
• Synthesis and Development of Photochromic Materials (Co-PI, SSP 134939; US$ 1,72,804/-)
  Duration: 1 Year (2014-2015)
  Funding Agency: SABIC (Industry Sponsored Project)
• Molecules to materials to devices for diagnostics – M2D (National Nodal Officer, CSC-0134; Rs. 831.45 Lakhs)
  Duration: 5 Years (2012-2017)
  Sponsoring Agency: CSIR (Chemical Cluster Mission Programme)
• Dye Sensitized Solar Cells (DSSC)/Quantum Dot Dye Sensitized Solar Cells (Principal Investigator & Project leader; CLP 133739; Rs. 119.00 Lakhs)
  Duration: 4 Years (2012-2016)
  Sponsoring Agency: Ministry of New and Renewable Energy (MNRE), Govt. of India
• Novel approaches for solar energy conversion under Technologies and Products for Solar energy Utilization through Networks (Team Member; TAP-SUN; NWP-54);
  Duration: 5 years (2011-2016)
  Sponsoring Agency: CSIR, India

• Ph. D., Chemistry, 2004, CSIR-NIIST, Trivandrum (University of Kerala, Trivandrum)
  Thesis title: “Synthesis and study of photophysical and DNA binding properties of viologen linked acridine and acridinium derivatives”
  Thesis supervisor: Dr. D. Ramaiah, Photosciences and Photonics Division, CSIR-NIIST, Trivandrum
• M. Sc. Organic Chemistry, 1999, School of Chemical Sciences, Mahatma Gandhi University, Kerala
  Thesis title: “Synthesis, photophysical and DNA binding studies of bisacridines”
  Thesis supervisor: Dr. D. Ramaiah, Photosciences and Photonics Division, CSIR-NIIST, Trivandrum
• B. Sc. Chemistry, Physics and Mathematics, 1996, Mahatma Gandhi University, Kerala

• Ph. D., Chemistry, 2004, CSIR-NIIST, Trivandrum (University of Kerala, Trivandrum)
  Thesis title: “Synthesis and study of photophysical and DNA binding properties of viologen linked acridine and acridinium derivatives”
  Thesis supervisor: Dr. D. Ramaiah, Photosciences and Photonics Division, CSIR-NIIST, Trivandrum
• M. Sc. Organic Chemistry, 1999, School of Chemical Sciences, Mahatma Gandhi University, Kerala
  Thesis title: “Synthesis, photophysical and DNA binding studies of bisacridines”
  Thesis supervisor: Dr. D. Ramaiah, Photosciences and Photonics Division, CSIR-NIIST, Trivandrum
• B. Sc. Chemistry, Physics and Mathematics, 1996, Mahatma Gandhi University, Kerala

• Dr. Sreejith M.
  Awarded Ph. D. in 2018
  Current Position: Post-Doctoral Fellow at Georgia Institute of Technology, Atlanta
  E-mail: [email protected]

• Dr. Sandeepa K. V.
  Awarded PhD in 2018
  Current Position: oLife Postdoctoral Fellow at Leiden University, Netherlands
  E-mail: [email protected]

• Dr. Silja AbrahamAwarded Ph. D. in 2017
  Current Position: Post-Doctoral Fellow at Georgia Institute of Technology, Atlanta, USA
  E-mail: [email protected]

• Mr. Mathews K. Manayani
  Joined as CSIR JRF in 2012
  Current Position: Assistant Proffesor in Nirmala College, Moovattupuzha
  E-mail: [email protected]

Google Scholar Profile:- http://scholar.google.co.in/citations?user=W3GOD0wAAAAJ
ORCID:- https://orcid.org/0000-0002-4592-8991

• DNA condensation triggered by the synergistic self-assembly of tetraphenylethylene-viologen aggregates and CT-DNA, Saraswathi, S. K.; Karunakaran, V.; Maiti, K. K.; Joseph, J., Front. Chem., 2021, 9, 716771 (https://doi.org/10.3389/fchem.2021.716771)
• Graphene quantum dots decorated with boron dipyrromethene dye derivatives for photodynamic therapy, Mangalath, S.; Saneesh Babu, P. S.; Nair, R. R.; Manu, P. M.; Krishna, S.; Nair, S. A.; Joseph, J., ACS Appl. Nano Mater., 2021, 4, 4162–4171. (https://doi.org/10.1021/acsanm.1c00486)
• Chemical-free and scalable process for the fabrication of a uniform array of liquid-gated CNTFET, evaluated by KCl electrolyte, Agarwal, P. B.; Thakur, N. K.; Sharma, R.; Singh, P.; Joseph, J.; Tripura, C., Sci. Rep., 2021, 11, 3979. (https://doi.org/10.1038/s41598-021-83451-2)
• A cross-linkable electron-transport layer based on a fullerene – benzoxazine derivative for inverted polymer solar cells, Vittala, S. K.; Ravi, R.; Deb, B.; Joseph, J., ChemPlusChem, 2020, 85, 1534-1541 (https://doi.org/10.1002/cplu.202000354)
• Sequence programmed DNA three-way junctions for templated assembly of fluorescent silver nanoclusters, Saraswathi, S. K.; Vittala, S. K.; Manayani, M. K.; Joseph, J., J. Photochem. Photobiol. B, Biol., 2020, 207, 111886. (https://doi.org/10.1016/j.jphotobiol.2020.111886)
• Nanosheets and 2D-nanonetworks by mutually assisted self-assembly of fullerene clusters and DNA three-way junctions, Vittala, S. K.; Saraswathi, S. K.; Ramesan, A. B.; Joseph, J., Nanoscale Adv., 2019, 1, 4158-4165. (http://dx.doi.org/10.1039/C9NA00485H)
• A three-component supramolecular nanocomposite as a heavy-atom-free photosensitizer, Kumar, P. P. P.; Yadav, P.; Shanavas, A.; Thurakkal, S.; Joseph, J.; Neelakandan, P. P., Chem. Commun., 2019, 55, 5623-5626. (http://dx.doi.org/10.1039/C9CC02480H)
• Novel Aza-BODIPY based turn on selective and sensitive probe for on-site visual detection of bivalent copper ions, Gawale, Y.; Mangalath, S.; Adarsh, N.; Joseph, J.; Ramaiah, D.; Sekar, N., Dyes Pigm., 2019, 107684. (https://doi.org/10.1016/j.dyepig.2019.107684)
• Rational synthesis of a polymerizable fullerene–aniline derivative: study of photophysical, morphological and photovoltaic properties$$^{S }$$§, Vittala, S. K.; Ravi, R.; Deb, B.; Joseph, J., J. Chem. Sci., 2018, 130, 135. (https://doi.org/10.1007/s12039-018-1547-8)
• Simple solution processable carbazole-oxadiazole hybrids for un-doped deep-blue OLEDs, Thurakkal, S.; Soman, A.; Unni, K. N. N.; Joseph, J.; Ramaiah, D., J. Photochem. Photobiol. A, 2018, 358, 192-200 (https://doi.org/10.1016/j.jphotochem.2018.03.012)
• Design and synthesis of solution processable green fluorescent D-pi-A dyads for OLED applications, Thurakkal, S.; Sanju, K. S.; Soman, A.; Unni, K. N. N.; Joseph, J.; Ramaiah, D., New J. Chem., 2018, 42, 5456-5464. (https://doi.org/10.1039/C7NJ04386D)
• Chiral self-assembly of fullerene clusters on CT-DNA templates, Kulala Vittala, S.; Joseph, J., Faraday Discuss., 2018, 207, 459-469. (https://doi.org/10.1039/C7FD00196G)
• Study on Liposomal Encapsulation of New Bodipy Sensitizers for Photodynamic Therapy, Gayathri, T.; Vijayalakshmi, A.; Mangalath, S.; Joseph, J.; Rao, N. M.; Singh, S. P., ACS Med. Chem. Lett., 2018, 9, 323-327. (https://doi.org/10.1021/acsmedchemlett.7b00490)
• Fullerene Cluster Assisted Self-Assembly of Short DNA Strands into Semiconducting Nanowires, Vittala, S. K.; Saraswathi, S. K.; Joseph, J., Chem. Eur. J., 2017, 23, 15759-15765 (https://doi.org/10.1002/chem.201703333)
• pH-Responsive Fluorescence Enhancement in Graphene Oxide-Naphthalimide Nanoconjugates: A Fluorescence Turn-On Sensor for Acetylcholine, Mangalath, S.; Abraham, S.; Joseph, J., Chem. Eur. J., 2017, 23, 11404-11409. (https://doi.org/10.1002/chem.201702198)
• Carbazole-Linked Near-Infrared Aza-BODIPY Dyes as Triplet Sensitizers and Photoacoustic Contrast Agents for Deep-Tissue Imaging, Gawale, Y.; Adarsh, N.; Kalva, S. K.; Joseph, J.; Pramanik, M.; Ramaiah, D.; Sekar, N., Chem. Eur. J., 2017, 23, 6570-6578. (https://doi.org/10.1002/chem.201605702)
• Transmissive-to-Black Electrochromic Devices Based on Cross-Linkable Tetraphenylethene-Diphenylamine Derivatives, Abraham, S.; Mangalath, S.; Sasikumar, D.; Joseph, J., Chem. Mater., 2017, 29, 9877-9881 (https://doi.org/10.1021/acs.chemmater.7b03319)
• Tuning of photoluminescence properties of functional phthalides for OLED applications, Shanmugasundaram, M.; Joseph, J.; Ramaiah, D., J. Photochem. Photobiol. A, 2016, 330, 156-162 (http://dx.doi.org/10.1016/j.jphotochem.2016.08.008)
• Selective recognition of cyanide ions by amphiphilic porphyrins in aqueous medium, Paul, A. K.; Karunakaran, S. C.; Jayaram, D. T.; Adarsh, N.; Joseph, J.; Ramaiah, D., J. Porphyr. Phthalocyanines, 2016, 20, 1368-1376. (https://doi.org/10.1142/s1088424616501133)
• Simultaneous binding of a cyclophane and classical intercalators to DNA: observation of FRET-mediated white light emission, Sanju, K. S.; Thurakkal, S.; Neelakandan, P. P.; Joseph, J.; Ramaiah, D., Phys. Chem. Chem. Phys., 2015, 17, 13495-13500. (https://doi.org/10.1039/c5cp00208g)
• Amino Acid-Porphyrin Conjugates: Synthesis and Study of their Photophysical and Metal Ion Recognition Properties, Paul, A. K.; Karunakaran, S. C.; Joseph, J.; Ramaiah, D., Photochem. Photobiol. 2015, 91, 1348-1355. (https://doi.org/10.1111/php.12527)
• Cross-Linkable Fluorene-Diphenylamine Derivatives for Electrochromic Applications, Abraham, S.; Ganesh, G. P. T.; Varughese, S.; Deb, B.; Joseph, J., ACS Appl. Mater. Interfaces 2015, 7, 25424-25433 (https://doi.org/10.1021/acsami.5b08218)
• Oxidative Thymine Mutation in DNA: Water-Wire-Mediated Proton-Coupled Electron Transfer, Barnett, R. N.; Joseph, J.; Landman, U.; Schuster, G. B., J. Am. Chem. Soc. 2013, 135, 3904-3914 (https://doi.org/10.1021/ja311282k)
• Oxidatively generated damage to DNA at 5-methylcytosine mispairs, Joseph, J.; Schuster, G. B., Photochem. Photobiol. Sci. 2012, 11, 998-1003. (https://doi.org/10.1039/c2pp05379a)
• One-electron oxidation of DNA: reaction at thymine, Joseph, J.; Schuster, G. B., Chem. Commun (Cambridge, U. K.) 2010, 46, 7872-7878. (https://doi.org/10.1039/C0CC02118K)
• Oxidation of DNA: damage to nucleobases, Kanvah, S.; Joseph, J.; Schuster, G. B.; Barnett, R. N.; Cleveland, C. L.; Landman, U., Acc. Chem. Res. 2009, 43, 280-287. (https://doi.org//10.1021/ar900175a)
• Oxidatively Damaged Nucleobases in Duplex DNA Oligomers: Reaction at Thymine? Thymine Mispairs, Joseph, J.; Schuster, G. B., J. Am. Chem. Soc. 2009, 131, 13904-13905 (https://doi.org//10.1021/ja9055917)
• Long-distance radical cation hopping in DNA: the effect of thymine-Hg (II)-thymine base pairs, Joseph, J.; Schuster, G. B., Org. Lett. 2007, 9, 1843-1846. (https://doi.org/10.1021/ol070135a)
• Steric effects on water accessability control sequence-selectivity of radical cation reactions in DNA, Cleveland, C. L.; Barnett, R. N.; Bongiorno, A.; Joseph, J.; Liu, C.; Schuster, G. B.; Landman, U., J. Am. Chem. Soc. 2007, 129, 8408-8409. (https://doi.org/10.1021/ja071893z)
• Emergent functionality of nucleobase radical cations in duplex DNA: Prediction of reactivity using qualitative potential energy landscapes, Joseph, J.; Schuster, G. B., J. Am. Chem. Soc. 2006, 128, 6070-6074 (https://doi.org/10.1021/ja060655l)
• Novel bifunctional viologen-linked pyrene conjugates: synthesis and study of their interactions with nucleosides and DNA, Hariharan, M.; Joseph, J.; Ramaiah, D., J. Phys. Chem. B 2006, 110, 24678-24686 (https://doi.org/10.1021/jp063079o)
• Photoisomerisation of dibenzobarrelenes—a facile route to polycyclic synthons, Ramaiah, D.; Sajimon, M. C.; Joseph, J.; George, M. V., Chem. Soc. Rev. 2005, 34, 48-57. (https://doi.org/10.1039/b300843f)
• Novel bifunctional acridine-acridinium conjugates: Synthesis and study of their chromophore-selective electron-transfer and DNA-binding properties, Kuruvilla, E.; Joseph, J.; Ramaiah, D., J. Phys. Chem. B 2005, 109, 21997-22002. (https://doi.org/10.1021/jp0543532)
• Tuning of intercalation and electron-transfer processes between DNA and acridinium derivatives through steric effects, Joseph, J.; Kuruvilla, E.; Achuthan, A. T.; Ramaiah, D.; Schuster, G. B., Bioconjugate Chem. 2004, 15, 1230-1235. (https://doi.org/10.1021/bc0498222)
• Design of Photoactivated DNA Oxidizing Agents: Synthesis and Study of Photophysical Properties and DNA Interactions of Novel Viologen Linked Acridines, Joseph, J.; Eldho, N. V.; Ramaiah, D., Chem. Eur. J. 2003, 9, 5926-5935. (https://doi.org/10.1002/chem.200304936)
• Control of electron-transfer and DNA binding properties by the tolyl spacer group in viologen linked acridines, Joseph, J.; Eldho, N. V.; Ramaiah, D., J. Phys. Chem. B 2003, 107, 4444-4450 (https://doi.org/10.1021/jp027248q)
• Steric and conformational effects on the photophysical and DNA binding properties of novel viologen linked tolylacridines, Eldho, N. V.; Joseph, J.; Ramaiah, D., Chem. Lett. 2001, 30, 438-439 (http://dx.doi.org/10.1246/cl.2001.438)

Patents awarded:

• Viologen linked acridine based molecule and process for the preparation thereof,D. Ramaiah, N. V. Eldho, and J. Joseph, UK Patent No. 2378440B dated November 30, 2005
• Viologen linked acridine based molecule and process for the preparation thereof,D. Ramaiah, N. V. Eldho and J. Joseph, US Patent No. 6630481 B2 dated Oct. 7, 2003.
• A process for the preparation of viologen linked acridine based molecule use as phototherapeutical and catalytic photoactivated DNA cleaving agents,D. Ramaiah, N. V. Eldho and J. Joseph, CSIR# 368/2000 dated 27/2/2001(INDIA)